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Many patients return to normal daily activities shortly after treatment, though individual recovery recommendations may vary

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Systemic Therapies: Reserved for Refractory Cases For patients with severe or refractory CHE, systemic therapies such as oral retinoids (e.g., alitretinoin) and immunosuppressants (e.g., cyclosporine, methotrexate) may be considered [91]

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Mammalian Sirt1: insights on its biological functions

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