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Ventral nail plate pigmentation originates from the distal matrix while the dorsal nail plate from proximal matrix.[21] The localization of pigment helps in selecting the anatomic site for exploration and biopsy, and can prevent a visible definitive nail dystrophy if the surgery is confined to the distal matrix[21] Pattern of melanonychiacomplete, longitudinal, or transverse

Journal of Aging Science

Although some side effects, predominantly related to nausea and vomiting, were observed, they were generally mild and temporary in nature

Excimer lasers, which use ultraviolet light to create pigment-producing cells, led to a significant increase in pigmentation in one small study of people with IGH