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As we age, our bodies experience a natural decline in NAD+ levels
The 20% reduction in major adverse cardiovascular events justifies long-term use even independent of weight loss effects
Its defining pharmacological characteristic relative to its predecessors (GHRP-2, GHRP-6) is its selectivity: at doses exceeding 200-fold the GH-release ED, ipamorelin does not stimulate significant release of adrenocorticotropic hormone (ACTH), cortisol, prolactin, FSH, LH, or TSH, in animal studies
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However, they remain useful for mechanistic insights, such as exploring AD molecular signaling and its connection with antidiabetic drugs
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