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Lack of insulin receptor signaling in Leprechaunism may result in the rare event of an alive but severely small for gestational age baby that will only survive if treated with recombinant-IGF-1 to substitute inulin receptor signaling with IGF1R signaling via their common intracellular pathways

For patients considering procedures such as SmartLipo or other body contouring surgeries, pre-operative weight loss achieved through GLP-1 treatments can enhance surgical outcomes

Modalities span checkpoint inhibitors, ADCs, CAR-T and targeted small molecules, with pipelines in protein degraders and bispecifics

The injectable vs oral peptides comparison explores the tradeoffs between delivery methods