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Most multivitamin supplements contain between 2.5 and 25 g of B12, which is well above the RNI but considered safe due to the vitamin's low toxicity profile

In cats, it is most common for B12 to be supplemented by a subcutaneous injection under the skin

Impure products can contain: Incomplete synthesis fragments that may cause immune reactions Bacterial endotoxins from contaminated manufacturing Heavy metals from poor quality synthesis reagents Misidentified or substituted peptides entirely Degradation products from improper storage before sale Users who experience unusual or severe side effects should consider source quality as a potential cause