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The frequency and nature of side effects can vary depending on the route of administration, with intramuscular injections occasionally producing different reactions compared to oral preparations

however, the broad-spectrum tissue tropism of COVID-19 raises the possible involvement of other host receptors in the binding of SARS-CoV-2 to other target tissue sites

Han X, Wang X, Chen X, Liu H, Liu J, Waye MMY et al (2024) Intervention efficacy of slightly processed allergen/meat in oral immunotherapy for seafood allergy: a systematic review, meta-analysis, and meta-regression analysis in mouse models and clinical patients