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Ascorbic acid can also directly enhance the catalytic activity of Tet methylcytosine dioxygenase 2 (TET2) in the oxidation of 5-methylcytosine (5mC), promote the folding and/or recycling of the cofactor Fe (2 + ) for TET2, and improve symptoms of depression (Ma et al., 2024
The proglucagon gene (gcg) encodes for glucagon as well as two glucagon-like peptides, GLP-1 and GLP-2 ( Figure 2 summarizes the tissue-specific post-translational processing of proglucagon by PC1/3 and PC2, the resulting peptide products, and their receptor targets
That said, monitor for any mood changes, especially in patients with pre-existing psychiatric conditions, and adjust psychiatric medications as weight changes (some psych med levels can be affected by significant weight loss)
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