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Here are some of the most commonly reported patterns: Difficulty falling asleep, even when tired Waking in the early hours (typically between 2am and 4am) and being unable to get back to sleep Night sweats that disrupt sleep, sometimes multiple times per night Lighter, more fragmented sleep feeling like you never reach deep sleep Waking feeling unrefreshed, regardless of how many hours you've been in bed Increased anxiety or a sense of dread around bedtime Restless legs or an uncomfortable urge to move your legs at night Needing to use the bathroom more frequently during the night (nocturia) If you're experiencing one or more of these regularly, it's worth speaking to your GP or a menopause-informed healthcare provider

In patients receiving tirzepatide, the downstream activation of GLP-1 and GIP receptor-mediated molecular pathways, especially in those with chronic pancreatitis, could increase the risk of developing pancreatic cancer [41]

Examples include antidepressants, heart medications, birth control pills, HIV medicines, and transplant drugs

Gut 66 (6), 10751082