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Participants were at least 18 years of age, spoke English fluently, and were not informed that the study specifically concerned weight, dieting, or GLP-1 medications prior to participation

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The proportion of controls decreased in the order of enterotypes A to D, whereas the proportion of severe PD increased in the same order, indicating that patients with severe PD tend to have specific enterotype(s) 75

for GLP-1R: native GLP-1 EC 50 : 0.0705nM, tirzepatide EC 50 : 0.934nM)