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Across 12 weeks of daily oral L-serine, we observed improvements in behavioral measures alongside more favorable Clinical Global Impression scores

HFHSD DKO mice were resistant to weight gain and accumulation of white adipose tissue compared to WT mice, which was unaffected by BA feeding

Similar results were observed when tumours were implanted into the flanks of mice, a result that suggests that this phenotype is not specific to the mammary gland environment (Extended Data Fig

doi: 10.1186/1471-2164-15-177 Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N