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HPCs isolated from Mat1a - / - mice transformed into fibroblastic cells when incubated with FGF10 and TGF-1, and these HPC-derived fibroblasts were significantly expanded in RRV-induced BA mouse model (102)

Point 2: Improved Firmness and Radiance in 2 Weeks 8.17% Increase in Skin Elasticity 18.96% Increase in Skin Radiance Point 3: Reduced Major Facial Wrinkles in 2 Weeks 6.37% Decrease in Fine Lines 8.78% Reduction in Crow's Feet The Improvement of 9, 62% in nasolabial folds

10.1016/j.anai.2021.02.026 Ann Allergy Asthma Immunol