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In situations such as the ones listed above in which the production of pro-oxidant molecules increase to a point where the antioxidant system cannot effectively remove them is when oxidative stress is known to occur

For example, in the GABA B receptor, heterodimers associate through C-terminal parallel coiled-coil -helices, and mutations in their primary structure can eliminate dimerization (White et al., 1998

Still, "the model that theyve set up, buying at a low cost and marking up at a very small amount, is very good for customers," Dusetzina said, particularly "people who are uninsured and many people who have health insurance but whose copays or whose share of the cost is causing them to have to pay too much." Hernandez said that for generic drugs, the copay can be more expensive than the actual price of the drug