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But your muscles still need fuel, especially on run days

The downregulation of OCTN2 activity and protein expression in the kidney reduces the reabsorption of carnitine in the kidney, leading to a decrease in carnitine availability in the liver and causing hepatic lipid metabolism disorders [260]

Investigators have examined its interactions with the hypothalamic-pituitary-adrenal (HPA) axis, stress response systems, and neuroendocrine signaling, as well as its apparent ability to cross the blood-brain barrier under certain experimental conditions

They are meant to supplement the diet and make up for any nutritional deficiencies that may occur as a result of factors like poor eating habits, lifestyle, or medical conditions