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Xanthine oxidoreductase in cancer: more than a differentiation marker

By bilaterally injecting lentiviral vectors carrying siRNA targeting GSK-3 into the hippocampal dentate gyrus region to modulate GSK-3 activity, the study found that IF promoted neuronal differentiation and maturation in the dentate gyrus and improved the known dysfunction in 3xTg-AD mice

This study was supported by the EHA Ukraine Bridge Funding awarded by the European Hematology Association, Ministry of Health of the Czech Republic (DRO - VFN00064165), National Institute for Cancer Research (EXCELES - LX22NPO5102), Ministry of Education, Youth, and Sports of the Czech Republic via Charles University (Cooperatio Program, research area Biology)

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