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: 1985) 109, no

(2022) aerobic exercise produces moderate to large improvements in overall cognitive function in healthy elderly individuals and patients with mild cognitive impairment (MCI), but is ineffective in dementia patients

The studies have suggested that under muscle stress the mature IGF-1 may become spliced as a response to stress and may thereby produce and release one of the isoforms called IGF-1EC, also known as Mechano Growth Factor (MGF)