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For the largest average weight loss among approved drugs, the comparison generally comes down to tirzepatide versus semaglutide, which we lay out in the best GLP-1 for weight loss

[DOI] [PubMed] [Google Scholar] 34.Faraonio R., Vergara P., Di Marzo D., Pierantoni M.G., Napolitano M., Russo T., Cimino F

Weekly weigh-ins at the same time under the same conditions (morning, after bathroom, before eating) provide trend data without the noise of daily fluctuations

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