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A synthetic gene circuit for self-regulating delivery of biologic drugs in engineered tissues

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Protocol 2: intensive 10-day cycle Goal: Concentrated telomerase activation with reduced injection frequency Duration: 10 days active, then 4-6 months off Schedule: Days 1-10: 10 mg epitalon subcutaneously, once daily at bedtime Days 11-180: Off cycle Repeat cycle 1-2 times per year Reconstitution: 10 mg vial plus 1 mL bacteriostatic water equals 10 mg/mL