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Sustained release was one of the first approaches to be assessed in clinical trials, and led to approval of the encapsulated formulation of exenatide: exenatide extended release (ER) (47)

However, LC and LAC lead to an increase in sperm motility compared to the control sample without time limitation

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(5) J Svensson, S Lall, S L Dickson, B A Bengtsson, et al (2000) The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats Journal of Endocrinology, 2000 Jun, Volume 165 (Issue 3), Pages 569-77