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Timely data also enables researchers to study new drugs as soon as patients begin taking them

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PAM activity was measured using a previously described radiotracer method (Additional file 1: Supplementary methods) in 24 heterozygous carriers of p.S539W, 27 heterozygous carriers of p.D563G and 21 homozygous carriers of p.D563G and age, sex and BMI matched non-carriers [24, 25]

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