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Description

153 A recent review provided a comprehensive overview of bacterial modification strategies and evaluated their potential applications in treating IBD

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Evidence that the Leucine plug contributes to tuning the force sensitivity of the NRR A striking feature of the structure of human Notch NRRs is a Leucine plug, a Leu moiety whose side chain is in position to block access to the cleavage site [1, 2, 5]

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