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The most relevant clinical aspects of these drugs are summarized in Table 10.7 Table 10.7 Clinically relevant metabolic effects of thiazolidinediones Contraindications of TZDs are Type 1 diabetes, liver disorders, and pregnancy, and the relative contraindications are Obese Type 2 diabetic patients 10.2.5 Alpha-glucosidase Inhibitors Two oral antidiabetic drugs, alpha-glucosidase inhibitors and lipase inhibitors, lower blood glucose modifying the intestinal absorption of carbohydrates and fat, respectively

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Research also documented elevated glutathione and ascorbic acid levels in GHK-Cu treated wounds