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A prior episode of acute pancreatitis on semaglutide should prompt a careful risk-benefit discussion before switching to tirzepatide rather than a straightforward transition

Acknowledgements This study was supported by Fondazione Cassa di Risparmio di Trieste to LM and ET and by a grant MIUR (PRIN 2010N8PBAA) to ET and is part of the collaborative consortium Italian Network on BDNF ( InBDNF )