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found comparable ACTH and cortisol responses between GHRP-2 and hexarelin (Ghigo et al., 1997)

This shows that natural homocysteine levels are a U-shaped curve in regard to all-cause mortality, but if there is an external reason for low homocysteine, such as excess NAC or B6, there is no statistically significant negative effect.[ref] Which brings us to the role of the gut microbiome in both low or high homocysteine

Thats why leaky gut is often associated with symptoms such as brain fog, difficulting concentrating, and even mood issues