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In this study, as amino acid precursors could be fed to improve concentrations of intracellular free l-cysteine, we resorted to overexpression of GK instead of loss-of-function mutations in GPR for accumulation of -glutamyl phosphate to strengthen the redirection of -glutamyl phosphate to GSH synthesis

Genetic Predispositions Affecting Glutathione Metabolism and Antioxidant Capacity Individual variations in genes encoding glutathione-related enzymesincluding glutathione S-transferases (GSTs), glutathione peroxidase (GPX), and gamma-glutamyltransferase (GGT)influence how efficiently your body produces, recycles, and utilizes glutathione

Sleep Medicine Reviews, 9(1), 25-39

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