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Studies using human aortic endothelial cells (HAECs), human vascular smooth muscle cells (HVSMCs) and mouse models have shown that TMAO treatment increases phosphorylation of p38, JNK and ERK1/2 [38, 132]

doi:10.1124/pr.119.018762

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Muscle fullness increases, pumps during training feel stronger, and strength gains begin accelerating