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If HCPCS codes are added to or deleted from an APC and, after ( recalibrating its relative payment weight, holding its unadjusted copayment amount constant results in a decrease in the coinsurance percentage for the reconfigured APC, the copayment amount would not change (unless retaining the copayment amount would result in a coinsurance rate less than 20 percent)

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For example, a strong T cell response has been described as ameliorating ADE of disease in a dengue model 139 and animal studies have suggested an aberrant T cell response to FI-RSV vaccination 33,114