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The Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure (DAPA-HF, NCT03036124) and Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Reduced Ejection Fraction (EMPEROR Reduced, NCT03057977) both demonstrated HF [48,49] and kidney benefits [50,51] in participants with HF and reduced ejection fraction with and without diabetes

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