Baseline thyroid labs (TSH, free T4) should be established before starting semaglutide, then rechecked at 6-8 weeks and 12 weeks, then every 3 months once stable on your maintenance dose
Those who use Ozempic can also encounter problems if there is a history of thyroid cancer, pancreatitis, kidney problems, or diabetic retinopathy
But on the other hand, if the agency sides with the compounders and reverses its decision on tirzepatides shortage status, it risks opening itself up to lawsuits from big pharmaceutical companies like Novo Nordisk and Eli Lilly, companies whose market dominance could be undercut by the production of compounded versions and who made billions of dollars in production investments to keep up with demand
Regarding inhibitory neurotransmission, researchers have identified atypical SNPs in genes associated with glutamate decarboxylase (GAD) and atypical copy number variations affecting GABA A receptor-associated genetic sites [11, 12]