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Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) represent one of the most transformative pharmacologic developments in metabolic medicine

Indicators of high risk include being 55 years of age or older with coronary, carotid, or lower extremity artery stenosis of more than 50% or with left ventricular hypertrophy

Bioengineered nanomedicines targeting the intestinal fc receptor achieve the improved glucoregulatory effect of semaglutide in a type 2 diabetic mice model

By directing the delivery of the NMDA receptor antagonist MK-801 via GLP-1 pathways, the researchers were able to influence neuroplasticity in the hypothalamus and brainstem