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The recently published phase-3 clinical trials data of the drug donanemab, which targets amyloid plaque, have shown to reduce cognitive decline in AD patients, but also cause brain haemorrhage (bleeding) and edema (swelling) in some of these patients

AAIC 2026 A comparative effectiveness analysis of second-line diabetes medications in realworld registry (Danish registry) comparing GLP-1 RAs to other agents found a protective effect of GLP-1 RAs vs certain other second-line drugs over 5 years, though not against all comparators

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, Boehringer Ingelheim group , Novo Nordisk A/S , Merck KGaA , Rhythm Pharmaceuticals Inc