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In the LEADER trial evaluating liraglutide, patients experienced a mean heart rate increase of approximately 3 beats per minute compared to placebo over the study duration

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Typical effects reported with these wellness therapies are usually mild and temporary, such as brief flushing or warmth, mild nausea if an infusion runs too fast, or minor irritation at an injection site, and a provider adjusts pacing and technique to keep them to a minimum