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Furthermore, establishing molecular probes and animal models to monitor SIRT1 activity in real time, along with NAD + level assessment, will help guide interventions and minimize adverse effects

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In addition to small-molecular antioxidants, extracellular antioxidant defense against ROS is also mediated by SOD mimetic compounds, capable of scavenging superoxide radicals and preventing the formation of damaging peroxynitrite, formed by the reaction between superoxide and nitric oxide