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Brunner S, Stecher L, Ziebarth S, et al

Please see, "Advisory Committees Give FDA Critical Advice and the Public a Voice," for more information

Apoptosis can be initiated via three principal pathways: the extrinsic (death receptor) pathway, the intrinsic (mitochondrial) pathway, and the endoplasmic reticulum (ER) stress pathway (Figure 2A)