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Beyond LPS, gut-derived components can also translocate through the bloodstream along this axis, a process that may exert a double-edged effect on uterine health

J Med Virol (2013) 85:21019

Iqirvo is intended to be used in combination with ursodeoxycholic acid (UDCA) in adult patients who have an inadequate response to UDCA, or as monotherapy in patients unable to tolerate UDCA