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A randomized controlled trial by Emmanuel et al.99 described evidence on the benefit of prucalopride in slow-transit constipation

Monitor for new thyroid symptoms as described earlier: new neck lumps, swallowing difficulty , persistent hoarseness, or unexplained shortness of breath

Epigallocatechin-3-Gallate attenuates microglial inflammation and neurotoxicity by suppressing the activation of canonical and noncanonical inflammasome via TLR4/NF-B pathway

Stroke recovery (the primary outcome) was monitored by behavioural tests (see ESM Methods: Assessment of stroke recovery): (1) a grip strength test, starting at 3 days after tMCAO, and weekly for 4 weeks, and (2) a corridor test, performed at weeks 1 and 4 after tMCAO (Fig