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Standard practice includes: Baseline thyroid function tests (TSH and free T4) before initiating GLP-1 therapy Repeat testing at 812 weeks after starting treatment or after dose escalation Regular monitoring every 36 months during active weight loss Return to annual monitoring once weight is stable and thyroid function remains consistent Adjustments to levothyroxine dosing may be necessary as weight changes

However, the pathophysiological mechanisms underlying its development remain unclear due to its multifactorial etiology, which encompasses genetic, environmental, and occupational factors

However, current clinical evidence indicates that GLP-1 receptor agonists do not directly cause these infections

the review is therefore not independent of the original developing group, and findings discussed in it should be evaluated together with the disclosures above