Potent NAC Formula: XYMOGEN NAC delivers 1200 mg of N-Acetyl-L-Cysteine per serving to support glutathione synthesis for antioxidant defense* Powerful Antioxidant Amino Acid: This amino acid supplement delivers a concentrated L-cysteine source for tripeptide glutathione production* Directions & Usage: Take one to two capsules twice daily between meals, or as directed by your healthcare practitioner Allergen-Conscious Purity: This NAC supplement is free from gluten, GMOs, dairy, soy, corn, peanuts, egg, and shellfish to fit seamlessly into a variety of dietary lifestyles XYMOGEN champions integrative health, empowering people and healthcare professionals with evidence-based formulations
(2019) 52:e12
McManus T
Introduction The hypothalamicpituitaryadrenal (HPA) axis is a critical neuroendocrine system that maintains homeostasis, particularly through its response to stress and its modulation of the immune system ( With aging, the HPA axis plays a pivotal role in stress response and immunomodulation ( Stress, defined as perceived threat to homeostasis, involves key components located in the hypothalamus (paraventricular nucleus), anterior pituitary gland, and adrenal glands, collectively forming the HPA axis ( Oxidative stress is associated with redox reactions involving hemoglobin (Hb), nitrite, and nitric oxide (NO), leading to the formation of highly toxic peroxynitrite when NO reacts with superoxide released during Hb autoxidation ( The primary role of cellular -glutamyltranspeptidase (GGT) is to metabolize extracellular reduced glutathione (GSH), facilitating intracellular GSH synthesis