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Of note, all of these patients had the following risk factors: phototype I or II, multiple melanocytic nevi, personal and family history of melanoma, regular use of tanning beds, and repeated exposure to sunlight

In addition to improving insulin resistance, a hypothesized mechanism in the progression of PD, in vitro and in vivo studies have shown that GLP-1 RAs can inhibit many pathways present in the pathogenesis of PD

Statistical analysis All data were expressed as the mean+/-S.E

Slices were sectioned cross- and length-wise (400 ) to ensure penetrability of the drug, using a Mcllwain tissue chopper (Brinkmann, Gomshall, UK) and transferred to a gassed (95% 0 2 /5% CO 2 ) incubation chamber containing aCSF for 90 minutes at room temperature