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Contents Descripcin General Sulfonilureas Meglitinidas Agonistas del Pptido Similar al Glucagn-1 Inhibidores de la Dipeptidil Peptidasa-4 Comparacin de Medicamentos Antidiabticos Referencias Descripcin General Diabetes Diabetes Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin

These agents directly block K ATP channels and stimulate insulin secretion in a high-glucose-independent manner, which can cause life-threatening hypoglycemia 5

The nasal cavity contains a highly vascularized epithelial surface, making it a valuable route for controlled peptide exposure in research models

accordingly, Bourron et al reported a case of amiodarone-induced thyrotoxicosis in a patient with 45 % weight loss following Roux-en-Y gastric bypass [57]