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Pregnant or breastfeeding women

Since these drugs affect how the body digests food, the first effects are on the gastrointestinal system

Novo Nordisk launched the 7.2 mg dose in the US in April 2026

two published tirzepatide case series (Naranjo "probable"), FAERS reporting odds ratio 22.55 for allodynia across GLP-1 with tirzepatides neuro-AE proportion lower than semaglutides, class cohort signal (aHR 2.15) in related agents