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While SGLT2 inhibitors often result in a weight loss of approximately 23 kg, no reduction in muscle mass or bone mineral density was observed with empagliflozin administration in the EMPA-ELDERLY study [9], which evaluated the effects of empagliflozin on glucose levels and muscle mass in Japanese patients with type 2 diabetes aged 65 years or older with a body mass index (BMI) of 22 kg/m or higher
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A Mayo Clinic summary of recent findings reported that the pattern may be explained by more frequent medical surveillance in people who start these medications
On day 2, the medium was changed to DMEM containing 10% FBS, 1% penicillin/streptomycin, and 1% bacterial extract or 10 g/mL linoleic acid (Merck, Germany)
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