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IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs

The PARP 1-17 family of poly-ADP ribose polymerases regulate DNA repair and nuclear stability

It is important to note that all scientifically verified effects described below are based on preclinical research, including in vivo rodent models and in vitro cellular systems

Experiments were performed based on animal ethics permit (BA02/2000-25/2021) by the Animal Welfare Committee of the University of Pcs and the Scientific Ethics Council for Animal Experiments, in accordance with the ARRIVE guidelines and the directives established by the European Communities council in 1986, in conjunction with the Law of XXVIII in 1998 governing animal care and use in Hungary