Our desensitization protocol was completed in 7 steps in approximately 3 h, with the aim of reaching the daily therapeutic dosage of exenatide
GLP-1 (Glucagon-like peptide-1) is a receptor agonist designed to help regulate hunger, slow digestion, and support steady, long-term weight managementall delivered through a convenient, physician-guided weekly injection
hypertension, type 2 DM, dyslipidemia) A meta-analysis of 22 trials involving over 17,000 patients determined that 50.2% and 17.5% of patients treated with GLP-1RAs (exenatide, semaglutide & liraglutide) experienced a weight loss of 5% and 10% compared to placebo, and that patients without type 2 diabetes achieved a significantly greater weight loss compared to those with diabetes (Vosoughi et al, 2022)
Meanwhile other research has shown that our GLP-1 levels may be closely linked to our gut microbiome [1,2]