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Inhibitors of CDK or those increasing the levels of CDK-inhibiting proteins constitute an intriguing group of pro-senescence compounds that can be utilized in anticancer therapy

55 Consequently, decreased levels of this CR1 may result in increased accumulation of inflammatory particles in the circulation, leading to potential inflammatory damage to the vasculature and surrounding tissues

A MiniTrap desalting column was used to change the buffer of the protein samples to 20 mM Na 2 HPO 4 , p H 7.5, 50 mM NaF, 5% ( w / v ) glycerol containing either 1 mM DTT or 0.5 mM GSH as reducing agents

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